Plaque Biofilm Management: Tailored – Comprehensive Oral Care Part C


НазваPlaque Biofilm Management: Tailored – Comprehensive Oral Care Part C
Дата конвертації30.04.2013
Розмір445 b.
ТипПрезентации


Plaque Biofilm Management: Tailored – Comprehensive Oral Care Part C

Prof. John G. Thomas, Ph.D.

Kerri Thomas, BS

West Virginia University

School of Dentistry















WHY???

  • Role of Dental Hygiene in Addressing Oral Biofilms

  • What are PRESENT anti biofilm tools???

  • What is a Students/Researcher perspective???

  • What are EMERGING anti biofilm tools



Tailored-Comprehensive Oral Care (T-COC) A Continuum from Birth to Death



Strategies in controlling the biofilm: HABITATS

  • Mechanical

    • Remove/reduce/disrupt habitat
    • Maintenance of Oral Hygiene
  • Chemical

    • Anti bacterial
    • Chlorexidine, Essential Oils, Triclosan,
    • etc…
    • Fluoride, Xylitol, Calcium, Phosphate

Pre/Probiotic



Present Oral anti biofilm Tools

Practice by habit???

ANTI-BIOFILM MOLECULES





Does size matter?



“Tooth Mousse” / Recaldent™ MI Paste

  • University of Melbourne

  • Casein Phospho-peptido-Amorphorus Calcium Phosphate (CPP-ACP)

  • Inhibits enamel and dentin demineralization

  • Slows progression of caries significantly

  • Adjunct to Fluoride Treatment

Rynolds EC. CPP-ACP – The Scientific Evidence. Adv. in Dental Res. 2009. 21; 25.

Emerging Oral anti biofilm Tools

Practice by science????

Oral Health Rinse

  • FDA Approved (Class II Device)

(8 Double-Blind Studies)
  • 0.2% Dilmophinol Hydrochloride

  • 1.5% Alcohol, 2x/Day

(All other oral anti-plaque/anti-gingivitis rinses are classified as drugs)
  • Prevents Adhesion

GUM PerioShield: www.sunstaramerica.com

Formerly John O. Butler Company



Peter Kropotkin

  • Viewed the theory of “survival of the fittest” as supporting co-operation rather than competition.

    • In his book Mutual Aid: A Factor of Evolution he set out his analysis leading to the conclusion that the fittest was not necessarily the best at competing individually, but often the community made up of those best at working together.
    • “The animal species, in which individual struggle has been reduced to its narrowest limits, and the practice of mutual aid has attained the greatest development, are invariably the most numerous, the most prosperous, and the most open to further progress."

The “We” View = Biofilm Phenotype

Probiotics: Definition (WHO, 2002)

  • Living microorganisms

  • Provide a benefit when administered in adequate amounts

  • Non-toxic

  • Food Additive OR Medical Management/ Intervention and position of the FDA



Prebiotics: An Overview

  • Functional Food Ingredients (Japan, 1980)

  • Non-Digestible

  • Beneficial Effects through

Selective Metabolism

  • Complementary to Probiotics



Probiotics: “What’s in a Name”

  • “Bacteriotherapy”

  • “Replacement Therapy”

  • “Competitive Exclusion”

  • “BioTherapeutics”

  • “Therapeutic Microbiology: Probiotics and Related Strategies.” ASM Press 8/2008. James Versalovic and Michael Wilson.

  • “A Prescription Engineered by Nature”

- Prof. John G. Thomas 10/2008

Tracking & Linking Disease by 6 Global Regions: The WHO Gradient - Probiotics





Mechanisms of Action Of Oral Probiotics





  Probiotic Strains



Various probiotic administrations for oral health





















PerioBalance® Daily Dental Probiotic  

Clinically shown to reduce plaque and promote healthy teeth and gums

New Paradigms THM

  • “Restorative Microbiology”

  • “Custodians” of Oral, Normal Flora

  • “Stewards” of Oral health /Oral Benifical Flora



WVUH Oral-Facial Microbiology Laboratory











Other Uses!!!!













Future of Biofilms and Probiotics And the Dental Office

  • Theragnostics: Dx/Rx

  • Tumor Detection

  • Tumor management .

  • Molecular medicine Enters the Mouth

  • Saliva vs Blood in Dx



“Half the world is composed of people who have something to say and can’t, and the other half who have nothing to say and keep on saying it.” -Robert Frost (1875-1963)





70!!!



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